Here's a video of FLCL stuff set to "It's the End of the World as We Know It," which sums it up nicely, I think. And here's one set to "Everlong." Completely different, also as true. It's a like a fruit, you slice it one way, you get apples, you slice it another way, you get tomatoes, you slice it a third way, you get a stapler. Not that you get to slice it.
It's about a kid who wants to skip adolescence and go straight to normal adulthood. Things should be ordinary...but they aren't. His dad's a perverted underground journalist, his brother's girlfriend wants hang out with him when she's not setting fires, his teacher is obsessed with chopsticks, and an intergalactic fugitive looking for the power of Atomsk has decided the kid should make a good portal for powers beyond his ken...also the guy chasing down the alien has nori for eyebrows. Really. No, really.
"Who are you, and what do you want?"
"I'm just a wandering housekeeper."
"Tell me the truth."
"I'm an alien."
"Yeah, and this afternoon, you were a nurse."
"Look at this. It's empty. There's no brain. Did you lose it somewhere?"
"Who is this? Your brother?"
"No, no relation. I'm from planet Earth."
"You are a million years under-evolved, primitive monkey!"
"That's discriminatory language used against underdeveloped planets."